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Kallopterolides A–I (1–9), a family of nine diterpenoids possessing either a cleaved pseudopterane or a severed cembrane skeleton, along with several known compounds were isolated from the Caribbean Sea plume Antillogorgia kallos. The structures and relative configurations of 1–9 were characterized by analysis of HR-MS, IR, UV, and NMR spectroscopic data in addition to computational methods and side-by-side comparisons with published NMR data of related congeners. An investigation was conducted as to the potential of the kallopterolides as plausible in vitro anti-inflammatory, antiprotozoal, and antituberculosis agents.more » « less
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Holt, Tina A.; Reddy, D. Sai; Huple, Deepak B.; West, Lyndon M.; Rodríguez, Abimael D.; Crimmins, Michael T.; Kutateladze, Andrei G. (, The Journal of Organic Chemistry)null (Ed.)
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